| NFL Week Five | Oct 6/18 |
| Alabama @ Ark +34 | Sat |
| Okla vs Texas +8 | |
| Kansas +29 @ West Va | |
| Maryland @ UM O/U 54 | |
| NW @ MSU O/U 48 | |
| LSU @ Florida +3 | |
| FSU +13 @ Miami-Fla | |
| Iowa St +11 @ Okla St | |
| KSU +5 @ Baylor | |
| Indiana +27 @ OSU | |
| Kentucky +6 @ Texas A&M | |
| Aub @ Missippi St +4 | |
| Wash @ UCLA +21 | |
| ND @ Va Tech +5 | |
| Cal +1 @ Arizona | |
| Utah +5 @ Stanford | |
| GB @ Lions O/U 51 | Sun |
| Jags +3 @ Chiefs | |
| Vikings +3 @ Eagles | |
| Over/Under 45 | |
| Raiders +6 @ Chargers | |
| Cowboys +4 @ Texans | |
| Over/Under 45 | |
| Redskins +7 @ Saints | Mon |
| Over/Under 52 | |
| TTech +3 @ TCU | Th |
| Over/Under 62* | |
| Eagles @ Giants +4 | |
| Over/Under 46* | |
| Falcons +3 @ Steelers | Sun |
| Dolphins +6 @ Bengals | |
| Ravens @ Browns +3 | |
| Cardinals +4 @ 49ers | |
| Red Sox @ Yankees | Mon |