| NFL Week Two | Sept 15/18 |
| Miami @ Toledo +11 | Sat |
| FSU @ Syracuse +3 | |
| Okla @ Iowa St +18 | |
| Vanderbilt +14 @ ND | |
| Duke +6 @ Baylor | |
| BYU +22 @ Wisconsin | |
| SMU @ Mich O/U 54 | |
| LSU +10 @ Auburn | |
| Boise St +3 @ Okla St | |
| Houston @ T Tech +1 | |
| Alabama @ Missippi +22 | |
| Middle-Tenn +34 @ Ga | |
| OSU @ TCU +13 | |
| USC +4 @ Texas | |
| Wash @ Utah +6 | |
| Fresno St @ UCLA +1 | |
| Chiefs +5 @ Steelers | Sun |
| Over/Under 52 | |
| Patriots @ Jags +2 | |
| Over/Under 45 | |
| Lions @ 49ers O/U 48 | |
| Giants +3 @ Cowboys | |
| Over/Under 42 | |
| Seahawks +3 @ Bears | Mon |
| Over/Under 44 | |
| Red Sox @ Yankees | Wed |
| Tulsa +2 @ Temple | Th |
| Jets @ Browns +1* | |
| Over/Under 43* | |
| Vikings +1 @ Packers | Sun |
| Panthers +6 @ Falcons | |
| Eagles @ Bucs +3 | |
| Raiders +6 @ Broncos | |
| Tulsa @ Temple O/U 52* | Th |